Lymphocyte cooperation is required for amplification of macrophage procoagulant activity.
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چکیده
منابع مشابه
Lymphocyte cooperation is required for amplification of macrophage procoagulant activity
Murine splenic lymphoid cells have been shown to possess basal procoagulant activity. This activity was localized to most macrophages by assay of cell populations, as well as by a direct plaque assay that permitted identification of expressed procoagulant activity of individual viable cells as well as content. Both content and viable expression of procoagulant activity was markedly increased by...
متن کاملO N Is Required for Amplification of Macrophage Procoagulant Activity
The biological diversity of the immune system is reflected in the variety of immune effector systems and mediation pathways that have emerged. Among the least recognized involve the hemostatic pathways. The possibility of cellular and molecular linkages between two host defense mechanisms, the hemostatic and immune systems, has long been suggested, but has yet to be satisfactorily delineated. T...
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The present experiments examine leukocyte procoagulant activity using mononuclear cell populations purified or enriched from rabbit bone marrow, blood, spleen, lymph node, thymus, and pulmonary alveoli. Cells from these six sites, obtained from control and endotoxemic animals and assayed without an intermediate culture step, were found to have procoagulant activity identified as tissue factor. ...
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ژورنال
عنوان ژورنال: Journal of Experimental Medicine
سال: 1980
ISSN: 0022-1007,1540-9538
DOI: 10.1084/jem.151.5.1232